InVivo Therapeutics Holdings Corp. 

One Kendall Square, Suite B14402 

Cambridge, MA 02139


October 20, 2020




Securities and Exchange Commission 

Division of Corporation Finance 

100 F Street, N.E. 

Washington, D.C. 20549


Re:         InVivo Therapeutics Holdings Corp. 

Registration Statement on Form S-1 

File No. 333-249353 

Request for Acceleration


Ladies and Gentlemen:


Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, InVivo Therapeutics Holdings Corp. hereby requests acceleration of the effective date of its Registration Statement on Form S-1 (File No. 333-249353), so that it may become effective at 9:00 a.m. on October 22, 2020, or as soon thereafter as practicable.


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  Very truly yours,
  By: /s/ Richard Toselli
  Name: Richard Toselli
  Title: President and Chief Executive Officer


Signature Page to Acceleration Request